Histopathological analysis of solitary thyroid nodules
Abstract
Objective: To determine the frequency of various thyroid disorders manifesting as solitary thyroid nodule.
Study design: Prospective analytical study.
Duration: January 2012 – June 2013
Setting: Histopathology department, Combined Military Hospital, Peshawar (Pakistan).
Methodology: Hundred specimens of solitary thyroid nodules were studied and their histopathological analysis was done.
Results: Out of 100 cases of Solitary thyroid nodules, 70 (70%) were non-neoplastic lesions and 30 (30%) were neoplastic lesions. Among 70 non-neoplastic lesions, 60 (85.71%) were adenomatous colloid nodules making it the most common lesion. Among 30 neoplastic lesions, 12 (40%) were benign and 18 (60%) were malignant. Among the malignant lesions, papillary thyroid carcinoma was the most common malignant neoplasm (66.7%).
Conclusion: Solitary thyroid nodules on histopathological analysis show a wide range of diagnosis from common non-neoplastic lesions like adenomatous colloid nodules to neoplastic lesions which can be benign or malignant. Adenomatous colloid nodule is the most common pathology detected in solitary thyroid nodules. The neoplastic lesions are comparatively less but with a significant proportion of malignancy.
Keywords: Solitary thyroid nodule, adenomatous colloid nodule.Downloads
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Copyright (c) 2016 Tariq Sarfraz, Humaira Tariq, Muhammad Javed Sawati, Adeel Arif, Saima Bashir
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