Histopathological analysis of solitary thyroid nodules

Authors

  • Tariq Sarfraz
  • Humaira Tariq
  • Muhammad Javed Sawati
  • Adeel Arif
  • Saima Bashir

Abstract

Objective: To determine the frequency of various thyroid disorders manifesting as solitary thyroid nodule.

Study design: Prospective analytical study.

Duration: January 2012 – June 2013

Setting: Histopathology department, Combined Military Hospital, Peshawar (Pakistan).

Methodology: Hundred specimens of solitary thyroid nodules were studied and their histopathological analysis was done.

Results: Out of 100 cases of Solitary thyroid nodules, 70 (70%) were non-neoplastic lesions and 30 (30%) were neoplastic lesions. Among 70 non-neoplastic lesions, 60 (85.71%) were adenomatous colloid nodules making it the most common lesion. Among 30 neoplastic lesions, 12 (40%) were benign and 18 (60%) were malignant. Among the malignant lesions, papillary thyroid carcinoma was the most common malignant neoplasm (66.7%).

Conclusion: Solitary thyroid nodules on histopathological analysis show a wide range of diagnosis from common non-neoplastic lesions like adenomatous colloid nodules to neoplastic lesions which can be benign or malignant. Adenomatous colloid nodule is the most common pathology detected in solitary thyroid nodules. The neoplastic lesions are comparatively less but with a significant proportion of malignancy.

Keywords: Solitary thyroid nodule, adenomatous colloid nodule.

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Published

03-08-2016

How to Cite

1.
Sarfraz T, Tariq H, Sawati MJ, Arif A, Bashir S. Histopathological analysis of solitary thyroid nodules. Pak J Pathol [Internet]. 2016 Aug. 3 [cited 2024 Apr. 18];23(3). Available from: https://pakjpath.com/index.php/Pak-J-Pathol/article/view/80

Issue

Vol. 23 No. 3 (2012)

Section

Articles

License

Copyright (c) 2016 Tariq Sarfraz, Humaira Tariq, Muhammad Javed Sawati, Adeel Arif, Saima Bashir

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