ALTERNATIVE STAINING TECHNIQUE FOR CERVICAL CYTOLOGY- A COMPARISON OF EFFICIENCY

Authors

  • Debasis Bhattacharya
  • Karabi Koner
  • B.B. Mukhopadhay
  • Tapan Kumar Ghosh

Abstract

Carcinoma of the cervix of the Uteri is one of the leading cause of morbidity and mortality world wide. In the developing countries it still remains the commonest malignancy among females. In the developed countries likeUSAandCanadathe screening programs for cervical carcinoma has been instituted and thereby these countries have reduced the incidence of cervical carcinoma.

In 1927, Papanicolau had introduced the special stain for cytology and after its introduction exfoliative cervico vaginal cytology has been extensively investigated and used as an important tool for screening of cervical carcinoma with an idea to reduce the incidence of carcinoma cervix. But screening for carcinoma cervix with Papanicolau staining is only possible if infrastructure and funds are available which is difficult for developing countries.

The aim of this study is to develop a low cost screening strategy for cervical cancer which will be cost effective while retaining sensitivity and specificity to perform screening technique. Several trials were done for screening procedure of cervical carcinoma. The present study was conducted basing on minimal invasiveness, easy to perform, acceptability to the subject, minimum cost and maximum efficacy. With the above background the study was conducted and comparison of cost, time and efficacy was done among Papanicolau, Haematoxylin and Eosin, May Grunwald Giemsa (MGG) and Giemsa staining. It was noticed that H&E staining has the lowest cost, easy and efficacious staining procedure for screening of cervical carcinoma, particularly for developing countries.

Key words: Cervical cancer, Pap smear, H and E staining, MGG staining, Giemsa staining, Cost effective.

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Published

03-08-2016

How to Cite

1.
Bhattacharya D, Koner K, Mukhopadhay B, Ghosh TK. ALTERNATIVE STAINING TECHNIQUE FOR CERVICAL CYTOLOGY- A COMPARISON OF EFFICIENCY. Pak J Pathol [Internet]. 2016 Aug. 3 [cited 2024 Mar. 28];20(4). Available from: https://pakjpath.com/index.php/Pak-J-Pathol/article/view/174

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