ALTERNATIVE STAINING TECHNIQUE FOR CERVICAL CYTOLOGY- A COMPARISON OF EFFICIENCY
Abstract
Carcinoma of the cervix of the Uteri is one of the leading cause of morbidity and mortality world wide. In the developing countries it still remains the commonest malignancy among females. In the developed countries likeUSAandCanadathe screening programs for cervical carcinoma has been instituted and thereby these countries have reduced the incidence of cervical carcinoma.
In 1927, Papanicolau had introduced the special stain for cytology and after its introduction exfoliative cervico vaginal cytology has been extensively investigated and used as an important tool for screening of cervical carcinoma with an idea to reduce the incidence of carcinoma cervix. But screening for carcinoma cervix with Papanicolau staining is only possible if infrastructure and funds are available which is difficult for developing countries.
The aim of this study is to develop a low cost screening strategy for cervical cancer which will be cost effective while retaining sensitivity and specificity to perform screening technique. Several trials were done for screening procedure of cervical carcinoma. The present study was conducted basing on minimal invasiveness, easy to perform, acceptability to the subject, minimum cost and maximum efficacy. With the above background the study was conducted and comparison of cost, time and efficacy was done among Papanicolau, Haematoxylin and Eosin, May Grunwald Giemsa (MGG) and Giemsa staining. It was noticed that H&E staining has the lowest cost, easy and efficacious staining procedure for screening of cervical carcinoma, particularly for developing countries.
Key words: Cervical cancer, Pap smear, H and E staining, MGG staining, Giemsa staining, Cost effective.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2016 Debasis Bhattacharya, Karabi Koner, B.B. Mukhopadhay, Tapan Kumar Ghosh
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Readers may “Share-copy and redistribute the material in any medium or format” and “Adapt-remix, transform, and build upon the material”. The readers must give appropriate credit to the source of the material and indicate if changes were made to the material. Readers may not use the material for commercial purpose. The readers may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.