Antimicrobial susceptibility pattern of methicillin resistant Staphylococcus aureus in a tertiary care setting- latest trend

Authors

  • Nadia Wali
  • Irfan Ali Mirza
  • Attiya Rasool
  • Amna Afzal
  • Bushra Sultan
  • Aamir Hussain

Abstract

Objective: To determine antimicrobial susceptibility pattern of methicillin resistant Staphylococcus aureus in a tertiary care setting.

Study design: Descriptive study

Place and duration of study: Microbiology Department, Armed Forces Institute of Pathology, Rawalpindi from March 2011 to April 2012.

Methodology: Two hundred isolates of MRSA recovered from various clinical specimens sent to AFIP for culture and sensitivity were identified using standard microbiological techniques and the antimicrobial susceptibility was carried out employing Kirby-Bauer disc diffusion technique as recommended by Clinical and Laboratory Standards Institute. The susceptibility pattern of isolates was recorded in percentages.

Results: Of the 200 MRSA isolated, all (100%) were susceptible to vancomycin & linezolid followed by 88% to tigecycline, 81% to chloramphenicol, 66% to amikacin, 62.5 % to clindamycin, 52.5% to doxycycline, 36% to trimethoprim-sulfamethoxazole, 29% to gentamicin, 28.5% to erythromycin and 26.5% to ciprofloxacin.

Conclusion: The results show that linezolid & vancomycin hold excellent in vitro efficacy against MRSA whereas doxycycline, clindamycin, trimethoprim-sulfamethoxazole, gentamicin, erythromycin & ciprofloxacin have poor sensitivity.

Key words: Antibiotic susceptibility. MRSA.

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Published

03-08-2016

How to Cite

1.
Wali N, Mirza IA, Rasool A, Afzal A, Sultan B, Hussain A. Antimicrobial susceptibility pattern of methicillin resistant Staphylococcus aureus in a tertiary care setting- latest trend. Pak J Pathol [Internet]. 2016 Aug. 3 [cited 2024 Apr. 16];23(1). Available from: https://pakjpath.com/index.php/Pak-J-Pathol/article/view/95

Issue

Vol. 23 No. 1 (2012)

Section

Articles

License

Copyright (c) 2016 Nadia Wali, Irfan Ali Mirza, Attiya Rasool, Amna Afzal, Bushra Sultan, Aamir Hussain

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