COMPARING THE EFFECT OF CHRONIC HYPERGLYCEMIA ON INTRA OCULAR PRESSURE IN DIABETIC PATIENTS

Authors

  • Uzma Ansari Pakistan Navy Ship (PNS) Shifa Hospital, Karachi Pakistan
  • Muhammad Kashif Hanif Pakistan Navy Ship (PNS) Shifa Hospital, Karachi Pakistan
  • Athar Iqbal Paracha Pakistan Navy Ship (PNS) Shifa Hospital, Karachi Pakistan
  • Qurratulain Combined Military Hospital, Murree Pakistan
  • Amina Tariq Pakistan Air Force Base, Jacobabad Pakistan
  • Sanam Haneef Combined Military Hospital, Lahore Pakistan

DOI:

https://doi.org/10.55629/pakjpathol.v33i4.721

Abstract

Objective: To compare the effect of chronic hyperglycemia on intra ocular pressure (IOP) in diabetic patients.

Material and Methods: This cross-sectional study was conducted at Pathology & Ophthalmology Departments of PNS Shifa Hospital, Karachi from February to May 2022. A total of 215 patients of Diabetes Mellitus having age between 40 to 70 years were included. HbA1c was used to categorize patients into two groups. Good glycemic control group (HbA1c <7%) and Poor glycemic control group (HbA1c >7%). IOP (mmHg) of both eyes was measured in both groups by applanation tonometer. Median comparison of IOP in both groups was done by Mann-Whitney U-test. To determine correlation between HbA1c levels and IOP, Pearson correlation was applied.

Results: Out of 210 patients 110(51.2%) patients had HbA1c < 7% while 105(48.8%) had HbA1c > 7%. Good glycemic control group had lower median IOP in both right (14.5 mmHg IQR 14-16) & left eye (15mmHg IQR 14-16) as compared to poor glycemic control group having median IOP in right eye (20mmHg IQR 19-22) & left eye (21 mmHg IQR 18-23). The difference was found to be statistically significant (p value <0.001). Pearson correlation showed a significant positive linear correlation between HbA1c and right eye IOP (r = 0.898, p value <0.01) and left eye IOP (r = 0.883, p value <0.01).

Conclusion: Patients with poor glycemic control had higher IOP as compared to good glycemic control. Chronic hyperglycemia is associated with raised IOP in diabetics.

Key Words: Diabetes mellitus, Intra ocular pressure, HbA1c.

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Published

30-12-2022

How to Cite

1.
Ansari U, Hanif MK, Paracha AI, Qurratulain, Tariq A, Sanam Haneef. COMPARING THE EFFECT OF CHRONIC HYPERGLYCEMIA ON INTRA OCULAR PRESSURE IN DIABETIC PATIENTS. Pak J Pathol [Internet]. 2022 Dec. 30 [cited 2024 Dec. 22];33(4):119-23. Available from: https://pakjpath.com/index.php/Pak-J-Pathol/article/view/721

Issue

Vol. 33 No. 4 (2022): Pakistan Journal of Pathology

Section

Articles

License

Copyright (c) 2022 Uzma Ansari, Muhammad Kashif Hanif, Athar Iqbal Paracha, Qurratulain, Amina Tariq, Sanam Haneef

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