ASSOCIATION OF NON-ALCOHOLIC FATTY LIVER DISEASE IN YOUNG HEALTHY ADULTS WITH DYSLIPIDEMIAS

Abstract

Objective: Present research work aims to assess association of fatty liver disease in young healthy adults with dyslipidemia.

Material and Methods: Present cross-sectional study was conducted at CMH Kharian, from January 2020 to January 2021. It included individuals with age of 20-30 years of either gender. In total 500 patients were screened for presence of fatty liver disease and hyperlipidemia. The demographics of the participants including age and gender were recorded. Blood samples of fasting participants were taken for lipid profile including total cholesterol, LDL, HDL and triglycerides. Moreover, liver transaminases were evaluated including aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels. Dyslipidemia was confirmed if any of lipid profile parameters were abnormal including total cholesterol (TC) more than 5.2 mmol, low density lipoprotein (LDL) more than 2.84 mmol, triglyceride (TG) more than 1.5 mmol and high-density lipoprotein (HDL) less than 0.9 mmol. Non-alcoholic fatty liver disease (NAFLD) was confirmed from ultrasonography.

Results: The mean age for participants was 24±2.9 years with age range of 21-28 years. Female participants were in majority (n=265; 53%) as compared to male participants (n=235; 47%). It is evident that 136(27.2%) patients comprised of both fatty liver disease and hyperlipidemia. Mean age for such patients was 23.76±2.89 years.

Conclusion: The co-existence of dyslipidemia and NFLD has been advocated.

Key Words: Dyslipidemia, Liver disease, Non-Alcoholic fatty liver disease.