SALIVARY GLAND TUMORS - A SEVEN YEARS STUDY AT ARMED FORCES INSTITUTE OF PATHOLOGY RAWALPINDI, PAKISTAN

  • Muhammad Asif Armed Forces Institute of Pathology, Rawalpindi (National Institute of Medical Sciences), Pakistan.
  • Sheza Malik Army Medical College Rawalpindi (National Institute of Medical Sciences), Pakistan
  • Ayesha Khalid Army Medical College (National University of Medical Sciences), Rawalpindi Pakistan
  • Madeeha Anwar Histopathology
  • Hafeez Ud Din Armed Forces Institute of Pathology, Rawalpindi (National Institute of Medical Sciences), Pakistan
  • Muhammad Tahir Khadim Armed Forces Institute of Pathology (National University of Medical Sciences), Rawalpindi Pakistan

Abstract

Objective:  To compare the frequency of benign and malignant tumors in the salivary gland.

Material & Methods: This Retrospective study was carried out at Histopathology Department, Armed Forces Institute of Pathology (AFIP) Rawalpindi, over a period of 7 years (Jan 2010 to 31st Dec 2016) including a total of sixty (n=60) major and minor salivary gland tumor cases, accessioned from 1st Jan 2010 to 31st Dec 2016. Descriptive statistics and frequencies were calculated with respect to age, gender, anatomical location and histopathological type. The data was analyzed using SPSS version 24.

Results: A total of 60 cases were included, out of which 29 were of male patients while 31 were of female patients. They were within the age range of 3 to 88 years. Mean age being 44.01 + 17.71 years. Benign tumors were more frequent (51.66%) than malignant (48.33%). The commonest anatomical site for benign tumor was parotid gland (54.84%), whereas for the malignant tumors it was submandibular gland (75.86%). Pleomorphic adenoma was found to be the most common benign tumor in both genders (93.75%, n=15 in females, 93.33% n=14 in males). Among the malignant tumors, the commonest one in the males was found to be mucoepidermoid carcinoma (42.9% n=6) which in turn was followed by adenoid cystic carcinoma and epithelial and myoepithelial carcinoma (14.3% each n=2). In the females, adenoid cystic carcinoma was the most prevalent tumor (46.7% n=7) followed by mucoepidermoid carcinoma (20% n=3). Benign tumor had a peak incidence at 51-60 years of age followed by 21-30 years. Whereas the malignant tumors, were the most prevalent within the age group of 61-70 years followed by 41-51 years.

Key Words:  Adenoid cystic carcinoma, Pleomorphic adenoma, Salivary gland tumors.

Published
2020-09-29