The frequency of uterine pathological changes in patients presenting with abnormal uterine bleeding between 45 to 65 years of age in hysterectomy specimens

Authors

  • Saba Aneeqa Foundation University and Medical College, Islamabad Pakistan
  • Faiza Kazi Foundation University and Medical College, Islamabad
  • Mumtaz Ahmed Foundation University and Medical College, Islamabad Pakistan
  • Irum Sohail Foundation University and Medical College, Islamabad Pakistan
  • Fatima Tul Zahra Michener College, Toronto Canada
  • Masood A Khan Foundation University and Medical College, Islamabad Pakistan

Abstract

Objective: To determine the frequency of various uterine pathological changes in hysterectomy specimens with clinical history of abnormal uterine bleeding.

Study Design: Cross sectional study.

Place and Duration of study: This study was done in the Department of Histopathology, Foundation University Medical College and Fauji Foundation Hospital Islamabad from 2nd Sep, 2016 to 2nd Mar 2017.

Material and Methods: 600 cases of hysterectomy specimens were included in the study in patients presented with abnormal uterine bleeding. The age ranges from 45 to 65 years.  After fixation of specimens, these were grossed according to standard protocol followed by processing and paraffin embedding. Slides were manually stained by a lab technician. The microscopic examination was carried by the trainee along with two consultants of histopathology.

Results: A total of 600 patients were included in the study. Mean age (years) of the patients was 50.91+5.76. Frequency of various pathologies in hysterectomy specimens was analyzed which included leiomyoma 189 (31.5%), adenomyosis 172 (28.7%), endometrial polyp 135 (22.5%), endometrial hyperplasia 48 (8.0), disordered proliferative endometrium 31 (5.2) followed by endometrioid carcinoma 25 (4.2).

Conclusion:  The study concludes that there were various frequencies of uterine pathologies in hysterectomy specimens. Most frequent causes of prolonged menorrhagia were leiomyoma, adenomyosis and endometrial polyp in the study.

Key Words: Abnormal uterine bleeding, Adenomyosis, Endometrial carcinoma and endometrial polyps.

Downloads

Published

12-11-2018

How to Cite

1.
Aneeqa S, Kazi F, Ahmed M, Sohail I, Zahra FT, Khan MA. The frequency of uterine pathological changes in patients presenting with abnormal uterine bleeding between 45 to 65 years of age in hysterectomy specimens. Pak J Pathol [Internet]. 2018 Nov. 12 [cited 2025 Apr. 1];29(2):30-3. Available from: https://pakjpath.com/index.php/Pak-J-Pathol/article/view/466

Issue

Vol. 29 No. 2 (2018)

Section

Articles

License

Copyright (c) 2018 Saba Aneeqa, Faiza Kazi, Mumtaz Ahmed, Irum Sohail, Fatima Tul Zahra, Masood A Khan

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Readers may “Share-copy and redistribute the material in any medium or format” and “Adapt-remix, transform, and build upon the material”. The readers must give appropriate credit to the source of the material and indicate if changes were made to the material. Readers may not use the material for commercial purpose. The readers may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.