ASSOCIATION OF VITAMIN D DEFICIENCY AND NEW ONSET TYPE-2 DIABETES MELLITUS

Authors

  • Sabahat Tariq Sheikh Zayed Hospital and Medical College, Rahim Yar Khan, Pakistan.
  • Zafar Majeed Sheikh Zayed Hospital and Medical College, Rahim Yar Khan, Pakistan.
  • Muhammad Tariq Ghafoor Sheikh Zayed Hospital and Medical College, Rahim Yar Khan, Pakistan.

Abstract

Objective: To determine the association between vitamin D status in newly diagnosed patients with type-2 Diabetes mellitus.

Study Design:  Comparative cross sectional study

Place & Period of Study: Department of Pathology and Department of Internal Medicine of Sheikh Zayed Hospital and Medical College, Rahim Yar Khan; from Januarary2015 to November 2015.

Method and Material: Ninety-seven newly diagnosed diabetics (subjects)and 93 non-diabetic persons (controls) were divided on the basis of their 25-hydroxyvitamin D3 (25OHD) levels in three groups, normal (>31 ng/ml), insufficient (20-31ng/ml) and deficient (<20ng/ml). 25OHD was measured by electrochemiluminescence using ­­­­­­­Cobas e 411. Their fresh Fasting Plasma Glucose (FPG) was also estimated by hexokinase method on Beckman coulter AU 480.

Results: Vitamin D levels were inversely correlated with frequency of diabetes mellitus (r=-0.20; p<0.01) with an Odd Ratio of 3.59 (95%confidence interval 1.29 to 8.70). Frequency of diabetes mellitus was significantly higher in vitamin D deficient patients as compared to patients with normal vitamin D status (p<0.05).

Conclusion: The chance of diabetes mellitus increases with worsening state of vitamin D.

Keywords: Vitamin D, Diabetes mellitus.

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Published

29-12-2016

How to Cite

1.
Tariq S, Majeed Z, Ghafoor MT. ASSOCIATION OF VITAMIN D DEFICIENCY AND NEW ONSET TYPE-2 DIABETES MELLITUS. Pak J Pathol [Internet]. 2016 Dec. 29 [cited 2025 Mar. 12];27(3). Available from: https://pakjpath.com/index.php/Pak-J-Pathol/article/view/364

Issue

Vol. 27 No. 3 (2016)

Section

Articles

License

Copyright (c) 2016 Sabahat Tariq, Zafar Majeed, Muhammad Tariq Ghafoor

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