Morphological changes in coronary arteries in cases of sudden cardiac death at high altitude

Authors

  • Hamid Shafiq
  • Furrukh Seir
  • Sajid M ushtaq
  • Muhammad Ashraf Sharif
  • Shahid Jamal
  • Nadira Mamoon
  • Shahid Hafeez
  • Farhan Tayyab

Abstract

Objective: To determine the changes in coronary arteries in patients dying at high altitude. Materials and Methods: Observational descriptive study was carried out at Armed Forces Institute of Pathology and Army Medical College Pathology Laboratory, Rawalpindi form 2002 to 2004 on autopsy of 58 cases dying at high altitude. Results: In 53 out of 58 cases, death was attributed to coronary atherosclerosis. The majority of cases were less than 40 years as also observed in people dying below high altitude. However triple vessel coronary atherosclerosis was seen in 67% cases and left anterior descending coronary artery was involved in almost 100% cases. Conclusion: Coronary atherosclerosis remains the major cause of death at high altitude in acclimatized individuals. Accelerated coronary atherosclerosis with triple vessel involvement in patients without prior history of ischemic heart disease points to specific indicators. Dietary modifications with high carbohydrate diet are recommended at high altitudes.

Downloads

Published

03-08-2016

How to Cite

1.
Shafiq H, Seir F, ushtaq SM, Sharif MA, Jamal S, Mamoon N, et al. Morphological changes in coronary arteries in cases of sudden cardiac death at high altitude. Pak J Pathol [Internet]. 2016 Aug. 3 [cited 2024 Dec. 22];17(2). Available from: https://pakjpath.com/index.php/Pak-J-Pathol/article/view/198

Issue

Vol. 17 No. 2 (2006)

Section

Articles

License

Copyright (c) 2016 Hamid Shafiq, Furrukh Seir, Sajid M ushtaq, Muhammad Ashraf Sharif, Shahid Jamal, Nadira Mamoon, Shahid Hafeez, Farhan Tayyab

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Readers may “Share-copy and redistribute the material in any medium or format” and “Adapt-remix, transform, and build upon the material”. The readers must give appropriate credit to the source of the material and indicate if changes were made to the material. Readers may not use the material for commercial purpose. The readers may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.