Vaginal carriage of K1 Escherichia coli in third trimester of pregnancy


  • Abdul Hannan
  • Hajra Azhar
  • Sidrah Saleem
  • Maryam Azam
  • Raima Rehman


Objective: To determine the vaginal colonization by K1 Escherichia coli in pregnant females.

Place and duration of study: Department of Microbiology, University of Health Sciences Lahore from September 2012 to March 2013.

Methodology: Samples from lower vagina were taken from one hundred pregnant women at 35 weeks or more of gestation visiting antenatal clinics of Lady Willingdon Hospital, Lahore. Lactose fermenting colonies were picked up from MacConkey agar plates and were identified with API 20E. Antimicrobial susceptibility of isolates was performed by Kirby-Bauer disc diffusion method according to Clinical Laboratory Standards Institute (CLSI) 2012 guidelines. K1 serotyping was performed by latex agglutination method.

Results: A total of 33 lactose fermenting gam negative rods were isolated from 100 vaginal swabs. Nineteen E. coli strains were identified out of 33 lactose fermanters, representing a vaginal colonization rate of 19%. Capsular K1 antigen was found in two (10.5%) of E. coli isolates.

Conclusion: 10.5% of K1 E .coli were found from amongst the E .coli (n=19) colonizing women in third trimester.





How to Cite

Hannan A, Azhar H, Saleem S, Azam M, Rehman R. Vaginal carriage of K1 Escherichia coli in third trimester of pregnancy. Pak J Pathol [Internet]. 2016 Aug. 3 [cited 2024 May 20];23(3). Available from: