Primary bone lymphoma (PBL) is comparatively rare disease process and distinct clinical entity. Previously reported most cases showed its particular tendency to affect senior adults. Although PBL can occur at any age and site with slight male predominance but femur bone has been reported the most commonly involved single site. Majority of PBL patients have early stage disease, and the stage 1 disease is the most important prognostic factor. Majority of the case series were reported from West with a little share from Asia including Japan. We report a case of DLBCL involving the upper end of humerus in a 22 years old male with review of literature.
Keywords: Primary bone lymphoma