INTRA-OPERATIVE CRUSH-SMEAR PREPARATIONS FOR DIAGNOSIS OF ENDOMETRIOSIS

Authors

  • Muhammad Qamar ul Haq Noor Combined Military Hospital Lahore (National University of Medical Sciences, Islamabad) Pakistan
  • Nadeem Zafar Combined Military Hospital Lahore (National University of Medical Sciences, Islamabad) Pakistan
  • Farrukh Ayub Combined Military Hospital Quetta (National University of Medical Sciences, Islamabad) Pakistan
  • Saerah Iffat Zafar Pakistan Air Force Hospital, Islamabad, Pakistan
  • Muhammad Sajid Yazdani Combined Military Hospital Chhor (National University of Medical Sciences, Islamabad) Pakistan
  • Amran Hafiz Combined Military Hospital Mangla (National University of Medical Sciences, Islamabad) Pakistan

Abstract

Objective: To determine the degree of success of intra-operative (per-operative) crush-smear preparations in endometriosis.

Study design: Comparative, prospective.

Place & Duration of Study: Departments of Pathology of six Armed Forces medical institutions (details in text) August 9, 2006 through July 31, 2016.

Materials and Methods: Eleven cases, ultimately turning out to be endometriosis, form the subject of this study. Each presented as painful mass of short duration and was radiologically suspected to be – among a host of various benign and malignant conditions – endometriosis. In either instance, per-operative microscopic consultation was deemed necessary. Frozen section facilities not being available, crush-smear preparations were made, stained instantly and communicated to the surgeon. Notably, rapid Romanovsky and haematoxylin-and-eosin (H&E) staining of smears takes 30% less than the time needed for a frozen section preparation.

Results: Without exception, all 11 specimens were reported as “benign, suggestive of endometriosisâ€. Histopathological examination of each excised specimen confirmed the diagnosis.

Conclusion: Pending further reports on the matter, it is thus far 100% accurate to explore the possibility of endometriosis by an intra-operative (per-operative) crush smear in the absence of a cryostat. It is advantageous over the latter method in being cheaper and quicker.

Key words: Intra-operative consultation, Crush-smear, Endometriosis

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Published

19-02-2017

How to Cite

1.
Noor MQ ul H, Zafar N, Ayub F, Zafar SI, Yazdani MS, Hafiz A. INTRA-OPERATIVE CRUSH-SMEAR PREPARATIONS FOR DIAGNOSIS OF ENDOMETRIOSIS. Pak J Pathol [Internet]. 2017 Feb. 19 [cited 2024 Mar. 29];27(4). Available from: http://pakjpath.com/index.php/Pak-J-Pathol/article/view/366

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